Targeting Behavioral Therapies to Enhance Naltrexone Treatment of Opioid Dependence
نویسندگان
چکیده
منابع مشابه
Pharmacological enhancement of naltrexone treatment for opioid dependence: a review
PURPOSE: Opioid dependence (OD) is a serious and growing clinical condition with increasing social costs that requires expanding treatment beyond opioid agonist substitution. The opioid antagonist naltrexone has displayed a remarkable association of theoretical effectiveness and poor clinical utility in treating OD due to noncompliant behavior and low acceptability among patients, only partly m...
متن کاملUsing behavioral economics to predict opioid use during prescription opioid dependence treatment.
BACKGROUND Research grounded in behavioral economics has previously linked addictive behavior to disrupted decision-making and reward-processing, but these principles have not been examined in prescription opioid addiction, which is currently a major public health problem. This study examined whether pre-treatment drug reinforcement value predicted opioid use during outpatient treatment of pres...
متن کاملInjectable, sustained-release naltrexone for the treatment of opioid dependence: a randomized, placebo-controlled trial.
CONTEXT Oral naltrexone can completely antagonize the effects produced by opioid agonists. However, poor compliance with naltrexone has been a major obstacle to the effective treatment of opioid dependence. OBJECTIVE To evaluate the safety and efficacy of a sustained-release depot formulation of naltrexone in treating opioid dependence. DESIGN AND SETTING Randomized, double-blind, placebo-c...
متن کاملA systematic review and meta-analysis of naltrexone implants for the treatment of opioid dependence.
INTRODUCTION AND AIMS Naltrexone implants are used to treat opioid dependence, but their safety and efficacy remain poorly understood. We systematically reviewed the literature to assess the safety and efficacy of naltrexone implants for treating opioid dependence. DESIGN AND METHODS Studies were eligible if they compared naltrexone implants with another intervention or placebo. Examined outc...
متن کاملTreating Opioid Dependence With Injectable Extended-Release Naltrexone (XR-NTX)
OBJECTIVES Once-monthly intramuscular extended-release naltrexone (XR-NTX) has demonstrated efficacy for the prevention of relapse in opioid dependence, providing an alternative to agonist or partial agonist maintenance (ie, methadone and buprenorphine). The question remains, for whom is this unique treatment most efficacious and can patient-treatment matching factors be identified? METHODS A...
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ژورنال
عنوان ژورنال: Archives of General Psychiatry
سال: 2001
ISSN: 0003-990X
DOI: 10.1001/archpsyc.58.8.755